Diabetic Complications - Can Benfotiamine Help Prevent Them?
Diabetic complications contribute too many life threatening diseases globally. The root cause of diabetic complications is elevated glucose levels which contribute to blood vessel damage. Diabetic retinopathy, nephropathy, or neuropathy are caused by damage to small blood vessel in the eyes, nerves and kidneys, etc. The bottom line of this damage is the lowering of the life expectancy of millions of diabetics worldwide.
What Can Be Done About It?
Few therapies are available today that treat diabetic complications. Most healthcare professionals recommend that their patients monitor their blood sugar by taking several blood readings a day to determine the amount of sugar in their blood. Blood sugar readings are generally higher from one to two hours after a meal.
It is suggested by these professionals that keeping blood sugar readings as close to normal as possible will reduce the onset of diabetic complications. Research has shown that there are four, chemical pathways that lead to diabetic complications. Instead of trying to explain these rather difficult chemical pathways, let the reader understand that diabetic complications are mainly caused by excess sugar in the cells, a condition known by the term advanced glycation endproducts (AGE) formation.
The research that was released in 2003 by a team of researchers from the Albert Einstein Collage of Medicine opened the possibilities that it may be possible to actually prevent and/or contain diabetic complications such as retinopathy, neuropathy and heart/circulatory conditions brought about by the presence of advanced glycation endproducts.
What Did This Research Suggest?
The Einstein researchers' work showed that a substance called, "benfotiamine", could reduce the effects of AGE by increasing the amount of an enzyme called transketolase. The research indicated that transketolase was increased by 300% which was enough to make a serious reduction of three of the four chemical pathways that open the door for diabetic complications in terms of vascular damage in diabetics. This vascular damage is directly responsible for the diabetic complications such as neuropathy, retinopathy and heart/circulatory conditions that lead to heart attack and stroke.
Can Benfotaimine Be Considered A Prudent Preventative?
Current research suggests that benfotiamine could possibly reduce the chances of diabetics developing the aforementioned complications. Many healthcare professionals readily recommend patients to add this nutritional supplement to their toolkit in the battle to prevent these insidious conditions that shorten the lives of thousands of diabetics annually.
Where Can I Find More Information About Benfotiamine?
More information about benfotiamine can be found by visiting the web site below and following the links. These links will give the reader a good base to make an informed decision about the use of benfotiamine in the battle against diabetic complications brought about by the presence of advanced glycation endproducts (AGE) which is excess sugar in the blood.
Research:
Hans-Peter Hammes, Xueliang Du, Diane Edelstein, Tetsuya Taguchi, Takeshi Matsumura, Qida Ju, Jihong Lin, Angelika Bierhaus, Peter Nawroth, Dieter Hannak, Michael Neumaier, Regine Bergfeld, Ida Giardino, Michael Brownlee. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nature Medicine 9, 294 - 299 (01 Mar 2003).
Michael Brownlee. Biochemistry and molecular cell biology of diabetic complications Nature 414, 813 - 820 (13 Dec 2001).
Roya Babaei-Jadidi, Nikolaos Karachalias, Naila Ahmed, Sinan Battah, Paul J. Thornalley. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine - Complications. Diabetes. (August 2003).
Zach Malott is CEO of Brentwood Health International, a nutritional supplement company involved in distribution and supplying wholesale, retail and end users.
Mr. Malott is available to discuss the research as it applies to benfotiamine in the treatment and prevention of diabetic complications such as neuropathy and retinopathy.
He can be reached at:
Phone: 505.354.0526
Website: http://www.emuhealthproducts.com
MORE RESOURCES:
 The Guardian | Diabetes quadruples birth defects risk, say researchers BBC News By James Gallagher Health and science reporter, BBC News The risk of birth defects increases four-fold if the pregnant mother has diabetes, researchers say. The Newcastle University study, published in the journal Diabetologia, analysed data from more ... Birth defect risk heightened by diabetic mums Diabetes 'increases birth defect risk' Women with diabetes warned to take precautions when having a baby |
 TucsonSentinel.com | Girl & dog bond over type 1 diabetes Tucson Citizen They each have Type 1 diabetes and have formed a bond which is helping to heal both. Petey, a 1 year old Terrier mix, came to the Humane Society of Southern Arizona as a stray. He was very skinny, and barely alive with a severely injured back leg that ... Girl and dog form healing bond |
 Science Codex | Diabetes study from Sanford-Burnham finds pancreas can 'taste' fructose Orlando Sentinel “We know a lot about how glucose interacts with the pancreas, but we didn't think the pancreas had much to do with fructose,” said Bjorn Tyrberg, adjunct assistant professor in the Diabetes and Research Center at Sanford-Burnham, and senior author of ... Pancreas May 'Taste' Fructose, Hinting at Links to Diabetes Tasting fructose with the pancreas |
 Waterbury Republican American | Paula Deen talks diabetes, recent controversy Fayetteville Observer By Jennifer Calhoun When celebrity chef Paula Deen announced she has was diagnosed with type 2 diabetes three years ago, no one seemed shocked. But many were frustrated, including local diabetes educators. After all, the down-home, Savannah-based ... A diabetes dialogue |
ACP Guideline Addresses Pharmacotherapy of Type 2 Diabetes Medscape February 6, 2012 — Metformin should be the initial drug for most patients with type 2 diabetes refractory to lifestyle modifications, with a second drug added if needed, according to a new clinical practice guideline from the American College of ... Metformin Preferred Drug for Type 2 Diabetes, Experts Say New Guideline: Metformin Best to Control HbA1c Metformin Is Type 2 Diabetes Drug of Choice |
Diabetes counsellors' crunch ails Bhopal Times of India BHOPAL: With an estimated two lakh people in the city having diabetes, there are barely a couple of diabetes counsellors, according to Centre of Diabetes and Obesity Management (CDOM). Experts view diabetic care not only in terms of equipment but, ... |
 Press TV | Diabetes takes toll on women's hearing Florida Today Diabetes is associated with hearing loss in women, especially if the blood sugar disease isn't well-controlled, new research indicates. The study, done by researchers at Henry Ford Hospital in Detroit, examined the medical records of 990 men and women ... Uncontrolled diabetes can cause hearing loss in women Study links diabetes, hearing loss in women |
Diabetes workshop can help people adjust to disease Fort Morgan Times By Luann Boyer Extension Agent If you have diabetes, reading nutrition labels is often frustrating and doing weekly food shopping can be downright overwhelming. Do you miss favorite foods which you believe are no-no's because of the amount of sugar and ... Medical Myth:Eating too much sugar causes diabetes |
The Curse of Amylin's Diabetes Drug Approval TheStreet.com ... after more than two and a half years, two FDA rejection letters, and at least a dozen amendments to the application, Amylin Pharmaceuticals(AMLN) received FDA approval for Bydureon, a once-weekly formulation of its existing diabetes drug Byetta. Amylin takes 4Q loss as Lilly partnership ends Amylin Pharmaceuticals Reports Fourth Quarter and Full Year 2011 Financial Results Inside Wall Street: Is Amylin a buyout target? |
Hypertension, diabetes rife in Ahmedabad: AMC survey Times of India AHMEDABAD: The entrepreneur Amdavadi across various economic strata now shows chronic signs of being both stressed and diabetic. In one of the recent comprehensive medical camps run by the Ahmedabad Municipal Corporation (AMC), for citizens across its ... |
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